Dietary oxalate and kidney stone formation

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منابع مشابه

Association between Dietary Diversity Score and Nutrient Adequacy in Patients with Calcium Oxalate Kidney Stone

Background: Nephrolithiasis is a global health problem that is growing exponentially in the developed and developing countries. This study aimed to determine the dietary diversity score (DDS) and its association with nutrient adequacy in patients with calcium oxalate kidney stone. Methods: The present cross-sectional study was conducted on 276 male patients with calcium oxalate kidney stone. Th...

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Protein-crystal Interactions in Calcium Oxalate Kidney Stone Formation

We have studied the ability of urinary molecules in altering the precipitation of kidney stone-related calcium oxalate monohydrate (COM) crystals and correlated the resulting morphologies with those of idiopathic COM kidney stones. We found that weakly acidic but highly glycosylated polyelectrolytes (Tamm Horsfall protein (THP), fetuinA, hyaluronic acid) do not significantly affect crystallizat...

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The Comparison of Major Dietary Patterns in People with and without Calcium Oxalate Kidney Stone: A Case-Control Study

Background: It was suggested that dietary patterns might play a role in the pathogenesis of nephrolithiasis. The aim of this study was to determine the relationship between dietary patterns and the occurrence of calcium oxalate kidney stone disease. Methods: A case-control study was conducted on 634 male and female participants aged 18-65 in Tehran using a convenient sampling method. The partic...

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Crystal surface adhesion explains the pathological activity of calcium oxalate hydrates in kidney stone formation.

Renal tubular fluid in the distal nephron of the kidney is supersaturated with calcium oxalate (CaOx), which crystallizes in the tubules as either calcium oxalate monohydrate (COM) or calcium oxalate dihydrate (COD). Kidney stones are aggregates, most commonly containing microcrystals of COM as the primary inorganic constituent. Stones also contain small amounts of embedded proteins, which are ...

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Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress

Males develop kidney stones far more frequently than females with a ratio of 2-3:1, suggesting that androgen receptor (AR) signaling might play a key role in the development of nephrolithiasis. Using the cre-loxP system to selectively knock out AR in glyoxylate-induced calcium oxalate (CaOx) crystal mouse models, we found that the mice lacking hepatic AR had less oxalate biosynthesis, which mig...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Renal Physiology

سال: 2019

ISSN: 1931-857X,1522-1466

DOI: 10.1152/ajprenal.00373.2018